Radiation-Induced Degradation of Polysaccharide Sodium Alginate
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Graphical Abstract
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Abstract
The radiation-induced degradation of sodium alginate by 60Coγ-rays was investigated in air at ambient temperature, and the change in their molecular weights was measured by multi-angle laser light scattering detector equipped with gel permeation chromatography (MALLS/GPC). The molecular weight of sodium alginate decreases with the increase of absorbed dose in the range of 0-60 kGy at the dose rate of 80 Gy/min. The dispersion of molecular weight distribution of sodium alginate becomes narrow along with the absorbed dose. The weight-average molecular weight (Mw) changes from 321 596.5 to 10 024 when the absorbed dose increases from 0 kGy to 60 kGy. It is found that the degraded sodium alginate with molecular weight peak of 6 000 is 83.22% of cumulative weight fraction. Anyway, the sodium alginate may have comprehensive application in the fields of agriculture, medicine and cosmetology as it can be absorbed well by biological tissue, if its weight-average molecular weight is below 10 000. It is also found that new components will be contained in the products of sodium alginate degraded by irradiation. The further study dealing with the checking the biological safety and purification shall be performed.
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