Abstract: To prepare 105℃ heat resistant PVC wire and cable, the ester of trimelliticacid are generally used by its plasticizer,for example TOTM and NODTM etc.,butthe price of this kind of plasticizer is higher. For the sake of depression ofquantity of TOTM, in present work, the effect of mixer of TOTM and ESBO(epoxide soyabean oil) on the properties of radiation crosslinked wire and cablefor 105℃ heat resistant PVC has been studied. From mechanical, electric proper-ties and thermal stability of wire and cable with different ratio TOTM/ESBO, itmay be known that the radiation crosslinked wire and cable will possess bettersynthetic properties, when the usable quantity of ESBO is an appropriate amount.