有临床应用意义的~(188)W/~(188)Re发生器的研制
Preparation of ~(188)W/~(188)Re Generator With a Clinical-meaning
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摘要: 对18 8 W / 188Re发生器的吸附条件及装柱工艺等进行了研究, 确定了最佳的吸附条件及吸附容量等重要参数, 制备了以酸性氧化铝为吸附剂的医用188W / 188Re发生器 ( 7 4 0GBq), 可用生理盐水淋洗得到188Re。188Re的淋洗效率在 3个月之内大于 70 %, 188W的漏穿率小于 10 - 4%, 核纯度和放射化学纯度均大于 99%。Abstract: A 188 W/ 188 Re generator with the activity of 7.40 GBq based on acid treated alumina is prepared for medical application. 188 Re can be eluted into vacuum vial with 0.9 % NaCl solution in the presence or absence of ascorbic acid. The elution yield of 188 Re is more than 70 % during a period of three months. The 188 W leakage is less than 10 -4 %. Both the radiochemical purity and radionuclide purity are more than 99 %.