Abstract: The blending of UO 2 and PuO 2 powders is the key technology in the MOX fuel manufactor. The Pu isotopic homogeneous, blending of UO 2 and PuO 2 and ball milling will be done in the blending process. In the paper, the House holder transform is applied to calculate the Pu isotopic homogeneous, and the track method is adopted to calculate speed of ball milling. All of the calculated results are accordance with the those from reference.