Abstract: The extraction behaviour of U(Ⅵ),Pu(Ⅳ),Am(Ⅲ),Eu(Ⅲ) and some other cations is investigated using amido podands, such as TBOPDA(N,N,N′N′ tetrabutyl 3 oxy pentandiamide) or a mixture of TBOPDA and N 503 (N, N′ diethylheptamide) as extractants, and 40 % octanol and kerosene as diluent for both cases. On the basis of tuble tests, courtcurrent experiments with miniature mix settler is carried out to separate U(Ⅵ),Pu(Ⅳ),Am(Ⅲ) and Eu(Ⅲ) from simulated high level liquid waste solution by the extractant of 0.075 mol/L TBOPDA+ 0.5 mol/L N 503/40 % octanol kerosene. In the coextraction battery, more than 99.9 % of U(Ⅵ), Pu(Ⅳ), Eu(Ⅲ) and Am(Ⅲ) is extracted into organic phase. 83 % of Pu(Ⅳ) and 36 % of Am(Ⅲ) are striped into aqueous in first back extraction battery, and in the second one the remaind Pu(Ⅳ),Am(Ⅲ) and Eu(Ⅲ) are striped completely. The results show that this flowsheet is highly effective on recover and group actinides and lanthanides from high level liquid waste.