可活化稳定同位素示踪中子活化分析法研究育龄妇女膳食铁的生物利用率

Study on Bioavailability of Dietary Iron of Women by Using Activable Isotopic Tracer and Neutron Activation Analysis Techniques

摘要: 采用两种浓缩丰度分别为 61 4%和 2 3 4%的可活化稳定浓缩同位素54 Fe和58Fe作为示踪剂, 结合中子活化分析法研究了北京地区健康育龄妇女膳食铁的生物利用率, 并以原子吸收分光光度法测定粪便排出的总铁和以不易被吸收的镝元素监测浓缩同位素铁在体内的滞留时间以确定不同试验者的粪便收集次数等多种途径来提高分析结果的可靠性。研究结果显示, 受试妇女膳食铁的生物利用率为(1 4 9± 3 9) %。

Abstract: The bioavailability of diet iron of 10 healthy young women in Beijing area is studied by using two enriched isotopes 54 Fe and 58 Fe, and neutron activation analysis techniques. The abundance of 54 Fe and 58 Fe is 61.4% and 23.4%, respectively. In additional, the atomic absorption spectrometry is employed to measure total iron in fecal samples. Dysprosium, rarely absorbed by human body, is used to monitor the residence time of tracer isotopes in order to collect the fecal samples completely. The results show that the bioavailability of dietary iron in young women is (14.9±3.9)%.