Abstract: Hydrogen-water liquid phase catalytic exchange bed was packed with “sandwich” layers of the catalyst and the packing, and the effects of catalyst carrier, inert packing and their filled ratio on the overall mass transfer coefficient(Kya) were investigated experimentally. The results show that C-PTFE is suitable for hydrophobic catalyst. Kya of the bed with catalyst-stainless steel mini-spiral packing is better than that with stainless steel θ-packing, and the active Al_2O_3 is not suitable for the exchange bed. Moreover, if the stainless steel mini-spiral packing is etched in aqua regia, the operating flexibility and overall mass transfer capability of exchange bed are improved notably. The preferable packing ratio (catalyst/packing) is 1∶4.