Abstract: In order to estimate the feasibility of alloy target slices fabrication technol-(ogy),some target slices were irradiated in-pile.The properties,such as appearance and size pre-and post-irradiation were tested.The preliminary results indicate that the connect between shell and the core and the containment of fission gas are in good condition for irradiated target slices,and there is no unfavorable influence on target slice handling caused by irradiation.