Abstract: It is reprocessing facility material development way that exploiture refractory metals replace extra-low-carbon stainless steel as spent fuel reprocessing facility material. Zirconium alloys display excellent corrosion resistance in reprocessing condition. Stress corrosion cracking of zirconium alloys in reprocessing condition is ameliorated through alloying treatment. Ti-5Ta titanium alloy has experimentation function in Tokai reprocessing plant of Japan, it is better in integration performance value. Ti-5Ta titanium alloy applying to reprocessing has the best foreground. Corrosion performance of Ti- 5%Ta-1.8%Nb titanium alloy exploited by India was investigated. It indicates the superior corrosion properties of Ti-5%Ta-1.8%Nb titanium alloy in comparison to the conventional stainless steel or nitric acid grade stainless steel.