125I短程治疗源剂量计算参数的蒙特卡罗确定

Determination of Dose Calculation Parameters of 125I Brachytherapy Source with Monte-Carlo Method

  • 摘要: 依据AAPM TG43U1推荐的剂量计算公式,针对6711型(3M)125I短程治疗源,用蒙特卡罗方法计算剂量率常数、径向剂量函数和各向异性函数的数值,并与已发表的相关数据进行了比较。其中,剂量率常数为0.986cGy·h-1U-1与TG43U1给出值相差2.31%;径向剂量函数数值与TG43和TG43U1均符合较好;随着角度和距离的增加,各向异性函数数值和TG43和TG43U1之间的符合程度趋佳。对径向剂量函数和各向异性函数进行拟合,得到实用性较强的经验公式。

     

    Abstract: According to dose calculation formalism recommended by AAPM TG43U1, dose rate constant, radial dose function and anisotropy function of Model 6711(3M) 125I brachytherapy source are calculated by Monte-Carlo method. Comparisons with relative data recommended by AAPM are performed. Dose rate constant, 0.986cGy·h-1U-1, within 2.31% compared to recommended value of TG43U1; values of radial dose function are in good agreement with TG43 and TG43U1; the agreement of anisotropy function with TG43 and TG43U1 is improved with increase of angle and distance. Experiential equations are obtained for radial dose function and anisotropy function by curve and surface fitting.

     

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