Abstract: By programming, and using thermophoretic deposition model, the thermophoretic deposition efficiency of the aerosol inside the containment, under various temperatures, pressures and particles diameter during severeaccidents of the pressurized water reactor was calculated. Through analysis, measurements are taken pertinently to depress the temperature of the inside wall of the containment, advance the thermophoretic deposition efficiency, and enhance the safety performance of the reactor at last.