基于蒙特卡罗模拟3-D PET图像重建的研究

3-D PET Image Reconstruction Based on Monte-Carlo Simulation

摘要: 应用蒙特卡罗模拟软件GATE对Ge Discovery LS PET/CT扫描系统进行模拟，获得三维投影数据，分别采用三维有序子集最大期望值法（3-D OSEM）与三维滤波反投影法（3-D FBP）进行图像重建，从空间分辨率、成像的对比度以及信噪比等方面对3-D OSEM法与3-D FBP法的重建结果进行比较。结果显示，对蒙特卡罗方法模拟获得的三维投影数据，采用3-D OSEM 法重建比3-D FBP法重建得到的图像质量好。

Abstract: hree-dimensional projection data for GE Discovery LS PET/CT system can be acquired by GATE, the Monte-Carlo simulation software. The image was reconstructed respectively by 3-D ordered subset expectation maximization (3-D OSEM) and 3-D filtered back projection (3-D FBP) from the 3-D projection data. We compared the results of 3-D FBP and 3-D OSEM in the spatial resolutions, image contrast and signaltonoise, etc. The results show that the image reconstructed by 3-D OSEM can provide better quality than by 3-D FBP for the 3-D projection data acquired by Monte-Carlo simulation.