Abstract: Gamma ray radiation and neutron radiation are predominant in the working conditions of BESⅢ, and the radiation-resistance aging of polyurethane pipes is very important in this condition, as the pipes of cooling liquid for beam pipe and SCQ (super-conducting quadrupole) vacuum pipe in BESⅢ. Polyester polyurethane pipes and polyether polyurethane pipes were irradiated by gamma ray and neutron. The radiation doses were as much as ten years’ doses in BESⅢ. Pressure test, FTIR and thermal analysis were used to study the radiation-resistance of these two kinds of polyurethane pipes. The results show that the radiation-resistance and thermal stability of polyester polyurethane pipes are prior to those of polyether polyurethane pipes, and the pressure resistance of polyester polyurethane pipes is almost maintained after the irradiation by gamma ray and neutron, but the polyether polyurethane pipes can be aged and ruptured after the irradiation by neutron.