Abstract: Dynamic reconfiguration is a technology by which control configuration can be updated without disturbance when the control system is in operation and is closely related to the architecture, control configuration and management mechanism of the control system. The characteristics of dynamic reconfiguration were studied and the intrinsic relationship between dynamic reconfiguration and control configuration standard was analyzed. Based on graphic configuration, the data engine model and its implementation independent of any control platform were presented, implying that the dynamic reconfiguration was converted to data-updating in the real data base of control station. Data engine was programmed by the multiagent system software. The method of dynamic reconfiguration in the programmable logic controller (PLC) and its application to the distributed control system in power generating units were described. The application of dynamic reconfiguration in NPP I&C system was also discussed.