Abstract: The paper utilizes many kinds of international reliability research methods, and summarizes the review of reliability research of Chinese nuclear power plant operators in past over ten years based on the simulator platform of nuclear power plant. The paper shows the necessity and feasibility of the research to nuclear power plant operators from many angles including human cognition reliability, fuzzy mathematics model and psychological research model, etc. It will be good to the safe operation of nuclear power plant based on many kinds of research methods to the reliability research of nuclear power plant operators.