Abstract: In this paper, based on the QCD factorization (QCDF), the soft-gluon exchange effect in D_s⁺→πK⁰ and D_s⁺→π⁰K⁺ decays was studied by using light-cone QCD sum rules. After taking the contribution from the correction of soft-gluon effect into account in the total decay amplitude, it is found that the final results of calculation are consistent with the latest experiment data.