Abstract: Mechanical test for transport package of radioactive material is one of the important tests for demonstrating package structure design. Drop test of package is a kind of destructive test. It is a common method of adopting the pre-analysis to determine drop orientation. Mechanical test of a sealed source package was calculated with finite element method （FEM） software. Based on the analysis of the calculation results, some values were obtained such as the stress, strain, acceleration and the drop orientation which causes the most severe damage, and the calculation results were compared with the results of test.