Abstract: Based on analysis of noble gas xenon monitoring data from Guangzhou radionuclide station, the validity of monitoring data was statistically analyzed. The statistical laws of activity concentrations and the minimum detectable activity concentrations of the four xenon isotopes 131Xem, 133Xe, 133Xem and 135Xe were preliminarily studied. The results show that activity concentrations and the minimum detectable concentrations of the four xenon isotopes follow Gaussian distribution. This work will help to evaluate monitoring threshold of the four xenon isotopes of radionuclide station and provide reference for the categorization of noble gas samples.