Abstract: The central control system (CCS) is the core of EAST experiment’s management system to coordinate all of subsystems according to pre-set value and logic. The upgraded CCS which is based on PXI (PCI extensions for instrumentation) bus devices and virtual instrument technology provides setting parameter and control to subsystems. The upgraded network also provides powerful support for the stable operation of the experiment. The new CCS has been applied to 2012 spring EAST campaign successfully, and it is proved to be stable and reliable.