Abstract: Micro nuclear battery is the perfect power of space craft equipment. ⁶³Ni is the core operation material of the ⁶³Ni battery. It can produce radioisotope ⁶³Ni while high abundance ⁶²Ni is irradiated in the reactor. In order to meet the requirements of the abundance and the purity, research of the separation for ⁶²Ni isotope was developed. The magnetic field and beam transmission status were simulated. The improvement designs of the ion source and the collector pocket were carried out. The process flow of high abundance ⁶²Ni using electromagnetic separation method was established. The experiment of ⁶²Ni isotope was developed by using electromagnetism isotope separator. The results show that the enrichment of ⁶²Ni isotope is more than 90%.