Abstract: An auto-loading facility for Na¹³¹I liquid medicine was introduced. The facility was installed in the 100-class clean shielding-box. The Na¹³¹I liquid can be loaded automatically in the vial accurately and sequentially, then, the rubber plug can be covered automatically. In the high radioactive circumstance, the facility has the advantages of mass subpackage and automatic production for radioactive liquid medicine, and also accords with the requirements of GMP.