Abstract: The polyimidazole/ordered mesoporous carbon composite with interpenetrating framework (AIM/OCMK-3) was prepared by functionalizing mesoporous carbon (OCMK-3) via radical polymerization. AIM/OCMK-3 was characterized by FT-IR, SEM and N-2 adsorption desorption techniques. The effects of different experimental parameters such as initial pH, initial concentration of U(Ⅵ), contact time and temperature on adsorption were investigated. The results show that AIM/OCMK-3 show the highest U(Ⅵ) adsorption capacity at initial pH of 4.0 and contact time of 30 min, and adsorption capacity increases from 40.90 mg/g to 213.01 mg/g after functionalizing. HCl is the preferred elution solution, AIM/OCMK-3 has good stability in the process of uranium in adsorption and desorption, and AIM/OCMK-3 can be reused.