用于制备高纯度123I的124Xe气体靶系统研制

Development of 124Xe Gas Target System for Production of High Purity 123I

  • 摘要: 在CIAE-30加速器上建立了用于制备高纯度123I的124Xe气体靶系统。该系统包括124Xe气体靶站和与之相连的30 MeV质子束流传输线、靶密封窗和束流线真空窗的He冷却循环系统、水冷却系统、靶腔真空系统、124Xe处理系统和123I化学处理系统,以及外围的124Xe气体保留系统、液氮传输系统、氦气配送系统和124Xe气体补充系统,还有辐射防护和检测系统、加速器束流调节、测量和气体靶控制系统。系统调试及批量试生产结果显示,该系统生产123I的批产能达111~148 GBq(3~4 Ci),产额大于296 MBq/(μA•h) (8 mCi/(μA•h))。123I核纯度大于99.8%,放化纯度大于95%,满足规模化生产的要求。

     

    Abstract: Using the CIAE-30 cyclotron, a 124Xe gas target system for the production of high purity 123I was established. This system includes 124Xe gas target station and the transmission line of the 30 MeV proton beam, the He cooling system for the sealed windows of target and beam-line, the water cooling system, the vacuum system for target chamber, the system for 124Xe processing and the system for the chemical processing of 123I. It also includes 124Xe retention system, LN2 transfer system, He gas transfer system and the system for 124Xe supplement, as well as the system for beam current adjusting, measuring and controlling, and the system for radiation protection and detection. The performance tests for the system, and the setting up of the conditions for the experiments prove that this system can offer 111-148 GBq (3-4 Ci) of 123I in one batch with a production rate greater than 296 MBq/(μA•h) (8 mCi/(μA•h)). The radionuclide purity of 123I is better than 99.8%, and the radiochemical purity is better than 95%, which fits the needs of the production in scale.

     

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