Abstract: The magnetism graphene oxide/β-cyclodextrin composite (MGO/CD） was prepared by the in-situ coprecipitation reaction in alkaline solution. The effects of pH value, adsorbent dosage, contact time and initial concentration of U(Ⅵ) were investigated by static adsorption experiment. The results show that the highest adsorption capacity is obtained at pH 6. The adsorption equilibrium time is 5 h. The kinetics and equilibrium adsorption are well described by pseudo-second-order kinetics and the Langmuir isotherm model, respectively. The maximum adsorption capacity for U(Ⅵ) is 322.6 mg/g at 30 ℃. Thermodynamic study reveals that the adsorption of U(Ⅵ) on MGO/CD is spontaneous and endothermic. SEM images show that MGO/CD has a rough surface and an uneven porous structure. FT-IR spectra demonstrates that hydroxyl group, carbonyl group and epoxide group are the main binding sites of U(Ⅵ) in MGO/CD. Desorption experiments indicate that the adsorption rate of MGO/CD is more than 95% after being employed 4 cycles.