肺部计数器虚拟校准结果的影响因素

武祯; 邱睿; 陈宜正; 李春艳; 李君利

doi:10.7538/yzk.2017.51.03.0529

肺部计数器虚拟校准结果的影响因素

武祯^1,2,
邱睿^1,3,4,
陈宜正^1,3,4,
李春艳^1,2,
李君利^1,3,4,*

1.
清华大学工程物理系,北京100084
2.
同方威视技术股份有限公司,北京100084
3.
清华大学粒子技术与辐射成像教育部重点实验室,北京100084
4.
清华大学高能辐射成像重点学科实验室,北京100084

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- 刊出日期: 2017-03-19

Influence Factor on Virtual Calibration Result of Lung Counter

WU Zhen^1,2,
QIU Rui^1,3,4,
CHEN Yi-zheng^1,3,4,
LI Chun-yan^1,2,
LI Jun-li^1,3,4,*

1.
Department of Engineering Physics, Tsinghua University, Beijing 100084, China
2.
Nuctech Company Limited, Beijing 100084, China
3.
Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Tsinghua University, Beijing 100084, China
4.
Key Laboratory of High Energy Radiation Imaging Fundamental Science, Tsinghua University, Beijing 100084, China

摘要

摘要: 内照射活体测量中，肺部计数器通常忽略肺以外其他器官中沉积的放射性核素对探测器计数的贡献，且校准使用的参考体模和被监测人之间会有身体形态的差异。本文利用中国成年男性体模库，采用蒙特卡罗程序模拟计算了⁶⁵Zn和⁶⁰Co核素的器官源探测效率，并计算了总探测效率，研究了这两个因素对虚拟校准的影响。结果表明，对于类似⁶⁵Zn的核素不能忽略肺部以外其他器官源的计数贡献；同一身高下，肺部计数器对⁶⁵Zn和⁶⁰Co核素的总探测效率随体重增加而降低，且对于⁶⁵Zn核素的降低比例会随摄入时间而变化；对于同一体模的总探测效率会随时间而降低。由此证明，核素生物动力学分布和体模形态的差异对肺部计数器总探测效率均有较大影响，且对不同核素影响会有不同。
- 虚拟校准 ,
- 体模库 ,
- 生物动力学模型 ,
- 探测效率
Abstract: In the in vivo measurement for internal contamination, the detector count from the radionuclides deposited in organs other than the lung is neglected for lung counter. Besides, the monitored people have morphological deviation with the reference phantom in calibration. The organ-specific detection efficiency for ⁶⁵Zn and ⁶⁰Co nuclides was simulated with Monte Carlo code by using the Chinese adult male phantom library, and the total detection efficiency was calculated. The effect of organ-specific detection efficiency and total detection efficiency on virtual calibration was studied. The results show that the contribution of nuclides like ⁶⁵Zn in the organs other than the lung can not be neglected in the virtual calibration. The total detection efficiency of the lung counter for ⁶⁵Zn and ⁶⁰Co nuclides decreases with the increase of weight at the same height, and the decreased proportion for ⁶⁵Zn varies with the time after intaking. For each phantom, the total detection efficiency decreases with the increase of time. The results prove that the radionuclide biokinetic distribution and morphological variation have a great influence on the total detection efficiency of the lung counter, which varies with nuclides.
- virtual calibration ,
- phantom library ,
- biokinetic model ,
- detection efficiency

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参考文献(18)

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肺部计数器虚拟校准结果的影响因素

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Influence Factor on Virtual Calibration Result of Lung Counter

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