Abstract: The transport container for radioactive materials is the unique physical barrier for the safe transportation of radioactive materials, and the container shall be able to resist against the possible collision accident. The corresponding mechanical tests are stipulated in GB 11806 and IAEA’S SSR-6 with regard to the accident scenes. Combining with test requirements prescribed in GB 11806 and SSR-6, the installations for drop impact mechanical tests of China Institute for Radiation Protection as well as stress, acceleration, deformation and image measurement system were introduced. By using the approach of combining the test with the finite element simulation for the transport container of 3 m³ uranium hexafluoride, transport container of XAYT-Ⅰ medical gamma knife therapy head and sealed radioactive sources and the transport container of ZHQY-QG-001 retired radiation sources, the application of deformation, stress and acceleration data of key parts of these containers was researched respectively in the safety performance assessment of the containers. The results show that the integrated application of finite element simulation technology and test technology can be used to analyze structure failure mode and safety assessment of packages, by collecting and analyzing the image data, stress data, acceleration data, deformation data, etc.