Abstract: The studies on the radiation effects of the vitrification for high-level radioactive waste were introduced. Defects induced by irradiation of α, β and γ rays in the vitrification and the corresponding analyzing methods were illustrated. The dependence of the defects concentrations on absorbed dose and the stability of the defects on temperature were exhibited. The changes in macroproperties of the different vitrifications with irradiation dose and the changes saturated were illustrated. The relationship between disorder and macroproperties of different vitrifications was introduced to explain the experimental results. The challenge in study on vitrification was introduced.