扫描式质子束剂量分布成像仪的研制及性能分析

Development and Performance Analysis of Scanning Proton Beam Dose Distribution Imager

  • 摘要: 在重离子癌症治疗技术中,保证重离子束的质量(均匀性、束斑大小和位置、能量等)非常重要。为满足临床对重离子束质量的要求,本文设计了一种新型质子束剂量分布成像仪。该剂量分布成像仪基于闪烁屏、镜面反射屏与光学信号采集装置,将重离子束通过硫氧化钆闪烁屏转化为可见光,通过采集可见光信号,对重离子束予以质量控制。同时通过精密的电动位移平台对闪烁屏、镜面反射屏与光学信号采集装置的相对位置进行遥控从而调整设备视野。结果表明,该剂量分布成像仪在布拉格峰后沿的能量分辨率为0.22 mm等效水深,空间分辨率为0.35 mm,对单一光源响应的均匀性在图像视野中心10 cm×10 cm的区域内为±3.5%,并可通过算法对测量结果进行修正。该剂量分布成像仪能完成对重离子束质量的各项关键指标的测试,可用于医用质子束的质量控制。

     

    Abstract: In the treatment of heavy ion cancer, it is very important to ensure the quality (uniformity, spot size and position, energy, etc.) of heavy ion beam. In order to meet the clinical requirements for the quality of heavy ion beam, a new proton beam dose distribution imager was designed. The dose distribution imager was based on scintillator, mirror reflector and optical signal acquisition device to transform the heavy ion beam into visible light through sulfur gadolinium oxide scintillator and collect visible light information to control the quality of the heavy ion beam. At the same time, the relative position of scintillator, mirror reflector and optical signal acquisition device can be remotely controlled through the precision electric displacement platform to adjust the equipment vision. The results show that the energy resolution of the dose distribution imager is equivalent water depth of 0.22 mm, the spatial resolution is 0.35 mm, the uniformity of response to a single source is ±3.5% in the 10 cm×10 cm area of the image field of view, and the numerical correction can be carried out by the algorithm. All of the above indicators meet the accuracy requirements of clinical medicine, and can be used for quality assurance of medical proton beam.

     

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