Abstract: The interaction between ultra-short ultra-intense laser and solid target could produce significant X-ray doses. The radiation protection problem is an interdisciplinary problem of radiation protection and laser plasma physics, which is essential for the safe operation of ultra-short ultra-intense laser device. In order to verify the dose calculation formula proposed by Tsinghua University, the X-ray dose generated by the interaction of ultra-short ultra-intense laser and solid target was studied through experiment. A shielding structure for shielding hot electron and scattered photon in the target chamber was designed so that only the X-ray dose generated by the interaction of hot electron and solid target was measured. The X-ray dose distribution at different angles was measured under different laser intensities (7×10184×1019 W/cm2) using XG-Ⅲ laser device. The measurement results were compared with the results from different dose evaluation formulas. The responses of different dose measurement detectors were also compared in this experiment. The experimental results show that the dose evaluation formula proposed by Tsinghua University is more consistent with the experiment results compared with the formula proposed in literature. With the laser intensity increase, the forward X-ray dose increases more rapidly than that in the lateral direction.