Abstract: Oxygen dispersion strengthened (ODS) ferrite/martensite (F/M) steel shows excellent radiation resistance due to the high sink strength and body-centered cubic structure matrix. It is considered as a candidate material for advanced nuclear energy systems and has become a research hotspot in the field of nuclear materials. Similar to other high strength materials, the strength of ODS steel increases while its toughness decreases, which is not benefit for the processing of complicated ODS steel components, and thus limits its engineering application. Achieving the strength-ductility trade-off of ODS F/M steel becomes a major challenging issue, however, the research about this issue is still not systematic and in-depth. Hence, the research status of the strength-ductility trade-off of ODS steel is summarized and analyzed in this paper, which provides research ideas for the strength-ductility trade-off of ODS F/M steel.