Abstract: In order to meet the needs of physical design of thorium molten salt reactor (TMSR) and physical analysis of thorium uranium fuel cycle for nuclear data, CENDL-TMSR-V1 library was developed by China Nuclear Data Center. The comparison between SCALE 6.1 built-in library and CENDL-TMSR-V1 library was performed by SCALE. The results show that for 1 GWt thorium molten salt breeder reactor, the maximum difference of keff between the two libraries is about 1 200 pcm within the burnup period. The sensitivity analysis of nuclear data to keff shows that the difference is mainly caused by the difference of graphite nuclear data. The result of the benchmark tests shows that the graphite nuclear data in CENDL-TMSR-V1 is more reasonable. Based on CENDL-TMSR-V1 44 groups covariance data library, the total uncertainty of nuclear data for keff at the beginning of life is 1.03%, which is about twice the calculation result of SCALE 6.1 built-in 44 groups covariance library, and the main difference is caused by the different covariance data of 233U, 232Th, etc.