Abstract: Unlike the traditional accelerator-driven subcritical system (ADS) using a metal target as the spallation neutron target, molten salt fuel is directly used as spallation neutron target in the target-integrated accelerator-driven subcritical molten salt reactors (AD-MSRs). Neutronics performance of the molten salt target has direct effect on the energy amplification factor of AD-MSRs, as well as the nuclear waste transmutation characteristic and fuel breeding efficiency. Therefore, a detailed study based on MCNPX was carried out on the spallation process of fluoride and chloride salt targets bombarded with high energy proton. The neutronics performances such as spallation neutron yield, spallation neutron energy spectrum, energy deposition distribution and spallation products produced by molten salt target were compared with liquid lead and lead-bismuth eutectic (LBE) targets. The calculation results show that the spallation neutron yield of molten salt target is lower than that of the liquid metal targets, but the gradient of the energy deposition distribution of the molten salt target is smaller, which is more favorable in terms of heat release at the target region. Compared with the liquid lead and LBE targets, the molten salt targets contain more gas fission products and high mass number alpha emit nuclei.