Abstract: Based on high-order Chebyshev rational approximation method (CRAM), a point-burnup code named ICRAM was developed and internally coupled to Monte Carlo code OpenMC, forming a burnup calculation and analysis program OPICE. Compared with the traditional partial fraction decomposition (PFD) form of CRAM, the high-order incomplete partial fractions (IPF) form of CRAM has the characteristics of good numerical stability, high calculation accuracy and better step tolerance, etc., which meets the needs of high-fidelity burnup calculation development. In order to improve the accuracy of coupling calculations, two coupling strategies including prediction-correction method and sub-step method were implemented in OPICE. Three different calculation modes were supported by OPICE to execute the decay, constant flux and constant power calculations. By calculating the OECD/NEA burnup benchmark and fast reactor burnup benchmark, the calculation results of OPICE are in good agreement with the experimental data and each reference value. The correctness and validity of OPICE are verified preliminarily.