Abstract: In order to study the flow heat transfer characteristics of liquid lead-bismuth eutectic alloy, the corresponding experimental bench was established, and the heat transfer characteristics test was carried out. A set of heat transfer relations for liquid lead-bismuth eutectic alloy were obtained based on the experimental data. At the same time, Fluent program was used to simulate the flow heat transfer of lead-bismuth eutectic alloy in a circular tube, so as to study the influence of different turbulence Prandtl number models and the selection of different turbulence models on the calculation results. Finally, based on the calculation results, the influence of different turbulence Prandtl number models on the calculation results was discussed, and the recommended physical models under different range of Peclet number were presented.