Abstract: The operation of transuranic nuclide nuclear facilities relates to low-energy X/γ rays, neutron, alpha particle and alpha aerosol. In view of its particularity and the main existing problems, breakthroughs have been made in the fields of site radiation monitoring, staff monitoring, environmental monitoring, etc. The aerosol real-time continuous monitoring device and method were established based on inductively coupled plasma mass spectrometry (ICP-MS). When the measurement time is 1 min, the limit of detection for ²³⁹Pu aerosol by the system is 1.7×10^-5 Bq/m³, which is far lower than the derived air concentration (DAC) limit (0.3 Bq/m³ and 1.0 Bq/m³ for M- and S-type ²³⁹Pu DACs respectively). A dose equivalent measurement system around the site based on cadmium-zinc-telluride (CZT) normal temperature semiconductor was established. The limit of energy for X/γ rays is as low as 15 keV, which meets the requirements for low energy X/γ rays detections. For the safety of personnel, a urine plutonium measurement method based on accelerator mass spectrometry (AMS) was established. The limit of detection for ²³⁹Pu is 1.1 μBq (0.47 fg), which is 2 orders of magnitude lower than the traditional α spectrometer measurement. At the same time, the established AMS system can measure environmental samples, etc.