Abstract: Steam generator, which is a connection between the primary and secondary circuits, plays an important role in pressurized water reactor (PWR) nuclear power plant. The heat transfer tube in steam generator is subjected to vibration induced by turbulence excitation. Unlike vortex shedding and fluidelastic instability, turbulence excitation induces small vibration amplitudes of the heat transfer tube. In order to stabilize the position of the heat transfer tube in the steam generator, the anti-vibration bars (AVBs) and corrugated belts are generally set. However, in the actual operation of steam generator, there will be contact and collision between heat transfer tubes and AVBs. This in turn will cause continuous damage to the heat exchange tube in the form of fretting wear, which may accelerate the failure of heat transfer tube. To investigate the collision behavior between the heat transfer tube and its support, the excitation experiments with cantilever-supported tube were carried out by changing the clearance from 0.05 mm to 0.25 mm, the exciting force from 0.4 N to 3.2 N, the natural frequency from 10 Hz to 16 Hz and the support forms (the AVBs and the corrugated belts). The results show that the normal root-mean-square displacements of the tube for both AVB and corrugated belt gradually slow down with the increase of the excitation force, while the tangential displacement of the AVB shows a linear increased tendency, which means a high risk of in-plane instability. Therefore, the support clearance should be minimized during the assembly process of the support and the tube to avoid collisions between adjacent tubes due to excessive amplitude. For the contact rates, they tend to be stable with the increase of the exciting force for both the AVB and corrugated belt. Note that the clearance between tubes and supports has a significant influence on the contact rates of the AVB. Under the impact-excitation predominant mode, the normal work rate positively depends on the exciting force. The impact of the clearance on normal work rate is relatively complicated. The normal work rate under the support of the AVB has peak values at 0.1 mm and 0.25 mm, while the corrugated belt only has a peak value at the clearance of 0.2 mm. This is caused by the coupling of contact force and displacement. The natural frequency of heat transfer tube has little effect on the vibration response results. This research can provide basic data and reference for the prediction of anti-wear life of heat transfer tubes under turbulent excitation.