Abstract: The integrated closed fuel cycle fast reactor nuclear energy system, which consists of metal fuel fast reactor and fuel regeneration facilities including fuel preparation, dry reprocessing and radioactive waste preparation, is an advanced stage in the development of fission energy. According to the positioning of the advanced nuclear fuel cycle system, how to determine the item layer design requirements of the integrated closed fuel cycle fast reactor nuclear energy system? The international evaluation of the fourth generation nuclear energy system has established the relevant methodology. IN this paper, combined with the fourth generation nuclear energy system evaluation methodology concerned about the economy, safety, sustainability and nonproliferation and other aspects, especially the user requirements related to the design, the item-level design requirements of the integrated closed fuel cycle fast reactor nuclear energy system are studied and proposed, and the design goals or indicators are set for the design of integrated closed fuel cycle fast reactor nuclear energy system.