Abstract: Through the integrated interpretation of element variation coefficient, R mode cluster analysis and factor analysis, the characteristic of element anomaly was analyzed using the basic geochemical data of stream sediment survey (1∶50 000) in Nanxiong area. Nanxiong area has good metallogenic potential for Bi, Mo, Pb, W, Au, Cu and Sn. According to the comprehensive analysis of some important parameters, such as the area, the average contrast and the sum of the normalized areal productivity of integrated anomaly, a scale of integrated anomaly was quantitatively ranked. With consideration of the geological background, three potential prospecting sectors were delineated, which are Miantuwo W-Mo-Cu, Yazizhai-Tianyaodi W-Mo-U, and Quan’an Sb-Pb.